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Artificial Intelligence

Penn Engineering AI

The Raj and Neera Singh Program in Artificial Intelligence

Through the Raj and Neera Singh Program in Artificial Intelligence, Penn Engineering offers transformative undergraduate and master’s programs that blend technical rigor with ethical training, preparing future leaders to drive innovation and responsibly shape the evolving AI landscape.

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Meet Our Expert Faculty

Our faculty members are dedicated to building up the next generation of engineers. In addition to being incredible mentors, they’re leading experts and researchers in their fields.

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George J. Pappas

UPS Foundation Professor of Transportation in Electrical and Systems Engineering
Director of the Raj and Neera Singh B.S.E. in AI Program

Chris Callison-Burch

Professor in Computer and Information Science

Director of the Raj and Neera Singh M.S.E. in AI Online Program

Rajeev Alur

Zisman Family Professor in Computer and Information Science

Founding Director of ASSET Center

Michael Kearns

National Center Professor of Management & Technology in Computer and Information Science

Founding Director of the Warren Center for Network and Data Sciences

René Vidal

Rachleff University Professor in Electrical and Systems Engineering
Director of the Innovation in Data Engineering and Science (IDEAS) Initiative

Duncan J. Watts

Stevens University Professor in Computer and Information Science
Principal Investigator of Penn Center on Media, Technology, and Democracy

Mark Yim

Asa Whitney Professor in Mechanical Engineering and Applied Mechanics
Ruzena Bajcsy Director of the GRASP Lab

AI Month 2026

AI Research at Penn Engineering

AI Uncovers New Antibiotics in Ancient Microbes

AI Uncovers New Antibiotics in Ancient Microbes

In a new study published in Nature Microbiology, researchers at the University of Pennsylvania used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics.

Reengineering AI to Target “Undruggable” Disease Proteins

Reengineering AI to Target “Undruggable” Disease Proteins

A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body.

Investing in Innovation

Investing in Innovation

Donors like Raj and Neera Singh are advancing AI education at Penn through philanthropy.

Lifesaving and More Cost-Effective Weather Predictions

Lifesaving and More Cost-Effective Weather Predictions

Paris Perdikaris, associate professor at Penn Engineering has developed Aurora, a foundation AI model that forecasts extreme weather and environmental events—faster and cheaper than traditional systems.

Meet Jean, Penn Engineering’s AI Tutor, Available 24/7

Meet Jean, Penn Engineering’s AI Tutor, Available 24/7

The chatbot is revolutionizing how students engage with coursework. Drawing on private course materials and discussion board data — resources commercial chatbots can’t access — Jean provides rapid, reliable answers.

How Penn is reimagining research in the age of artificial intelligence

How Penn is reimagining research in the age of artificial intelligence

The AI x Science Fellowship builds on IDEAS (Innovation in Data Engineering and Science) Center to support cross-disciplinary research across the University

Penn Engineers First to Train AI at Lightspeed

Penn Engineers First to Train AI at Lightspeed

Penn Engineers have developed the first programmable chip that can train nonlinear neural networks using light — a breakthrough that could dramatically speed up AI training, reduce energy use and even pave the way for fully light-powered computers.

Evaluating Large Language Models for Cyberbullying Behavior

Evaluating Large Language Models for Cyberbullying Behavior

Ph.D. students in Penn’s Brachio Lab have been assessing the safety of machine learning systems for real-world uses like economic forecasting, cultural politeness, and legal reasoning.

Combining AI and Art-making for Youth Well-being

Combining AI and Art-making for Youth Well-being

Through a community-led partnership project, graduate student Eileen Feng and an interdisciplinary, cross-school team are working with local youth to tailor an AI-supported platform for healing through creative arts.

What is an NPU? A Penn Expert Explains

What is an NPU? A Penn Expert Explains

Increasingly, neural processing units (NPUs) are making their way into consumer electronics: laptops, high-end tablets, phones, and more. But what do they do, and why are they suddenly showing up?

AI Uncovers New Antibiotics in Ancient Microbes

AI Uncovers New Antibiotics in Ancient Microbes

In a new study published in Nature Microbiology, researchers at the University of Pennsylvania used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics.

Reengineering AI to Target “Undruggable” Disease Proteins

Reengineering AI to Target “Undruggable” Disease Proteins

A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body.

Centers + Institutes

Affiliated centers foster interdisciplinary AI research and collaboration across the university.

AI-Enabled Systems: Safe, Explainable and Trustworthy

The Warren Center

For Network & Data Sciences

Innovation in Data Engineering and Science

The PRECISE Center

Penn Research In Embedded Computing and Integrated Systems Engineering

AI x Science

Postdoctoral Fellows collaborate across disciplines

Empowering Futures

Empowering Futures

How PRECISE Center’s Mentorship with Google is Transforming Academic Careers and Innovation

Zixuan Yi

A "Question-Driven" Approach to Improving AI and Machine Learning

The ASSET Center

The ASSET Center

Advances Trustworthy AI with Support from AWS

PRECISE Center

Unlocking Multi-Core Potential: Robert Gifford’s Breakthroughs in Real-Time System Safety

Innovation & Impact Podcast

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From left: Benedetto Vigna, CEO of Ferrari, and Vijay Kumar, Nemirovsky Family Dean of Penn Engineering and Professor of Mechanical Engineering and Applied Mechanics, during a podcast recording at AI Month. (Credit: Sylvia Zhang)

Episode 12

Driving the Future with Benedetto Vigna

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From left: Jason Cong, Distinguished Professor in Computer Science and Electrical and Computer Engineering at UCLA’s Samueli School of Engineering and Vijay Kumar, Nemirovsky Family Dean of Penn Engineering and Professor in Mechanical Engineering and Applied Mechanics (Credit: Sylvia Zhang)

Episode 11

Designing the Future of AI and the Next Era of Computing

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Episode 7

The Future of AI with Yann LeCun

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