AI Uncovers New Antibiotics in Ancient Microbes News / August 14, 2025 In a new study published in Nature Microbiology, researchers at the University of Pennsylvania used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics. Read More
Reengineering AI to Target “Undruggable” Disease Proteins News / August 14, 2025 A study published in Nature Biotechnology reveals a powerful new use for artificial intelligence: designing small, drug-like molecules that can stick to and break down harmful proteins in the body. Read More
Understanding the Cellular Mechanisms Driving Solid Tumors’ Robust Defense System News / February 5, 2025 In a joint research project involving experts from different fields, researchers Michael Mitchell, Wei Guo, and Drew Weissman discovered that solid tumors can create a barrier that prevents drugs from reaching them, similar to a protective force field. Read More
Missing the Microbiome: Uncovering New Antibiotics Inside the Human Gut News / February 5, 2025 Penn Engineering and Stanford researchers leveraged AI to discover dozens of potential new antibiotics in the human gut microbiome. Read More
Empowering Future Engineers: Lyle Brunhofer and the Impact of Senior Design News / February 5, 2025 Lyle Brunhofer (EAS’14, GEng’14) advises companies on digital transformations, applying the skills he learned at Penn Engineering to modernize firms’ understanding of customers in industries as diverse as pharmaceuticals and consumer products. Read More
